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| Product Name: |
Camptothecin Extract
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| Supply Ability: |
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| Related proudcts |
herbal extract, camptothecine, |
| Specifications |
Appearance: Light yellow needle crystal |
| Price Term: |
FOB |
| Port of loading: |
shanghai |
| Minimum Order |
10kg |
| Unit Price: |
US$20-100/KG |
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Information
Active Ingredient: Camptothecin by HPLC
Appearance: Light yellow needle crystal
Botanical source: Camptotheca acuminata Decne
Storage: stored in cool & dry place, keep away from strong light and heat
Description
Camptothecine is an alkaloid derived from the Chinese tree Camptotheca acuminata Decne. Camptothecine and its derivative are unique in their ability to inhibit DNA topoisomerase I, by stabilizing a covalent reaction intermediate termed the cleavable complex which ultimately causes tumor cell death. In clinical it is widely believed that camptontheic analogs exhibited remarkable anti-tumour and anti- leukaemia activity. Topoisomerase is a kind of important enzyme during DNA reproduction Process, in charge of the winding and unwinding of the chains that make up the chromosomal DNA Superhelix structure. If the chromosome cannot be unwound, transcription of DNA message cannot occur and the protein cannot be synthesized, which ultimately causes cell death. Application of camptothecin in clinic is limited due to serious side effects and poor water-solubility. At present, some camptothecin analogs, either semi-synthetic or synthetic drug based on camptothecin, have been applied cancerous therapy such as topotecan and irinotecan while other have been obtained satisfying curative effects in clinic.
Medicinal Function
1ˇ˘Anti-tumor, anti-virus;
2ˇ˘Immunosuppressive;
3ˇ˘Anti-early pregnancy;
4ˇ˘The process of changing the skin epidermal keratinocytes;
Clinical application: for cancer, psoriasis, warts treatment, acute and chronic leukemia and Hepatosplenomegaly caused by schistosomiasis, etc.
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| Company: |
Xi'an Shengtian Biological Engineering Co., Ltd.
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| Contact: |
Mr. nick yan |
| Address: |
Room 12803,Unit2,Mudan Building,Kunming Road,Lianhu District,Xi'an,China. |
| Postcode: |
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| Tel: |
+86-29-63683543 |
| Fax: |
+86- 29-84492601-8008 |
| E-mail: |
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